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Q58 (CGS/2026) Science & Technology › Basic Science (Physics, Chemistry, Biology)

Which of the following cells in the human digestive system is responsible for secretion of hydrochloric acid in the stomach?

Result
Your answer: —  Â·  Correct: A

Explanation

In the human digestive system, the gastric glands located in the mucosa of the stomach contain several types of secretory cells. Parietal cells (also known as oxyntic cells) are responsible for the secretion of hydrochloric acid (HCl) and intrinsic factor, which is essential for the absorption of Vitamin B12. The HCl creates an acidic medium (pH 1.8) necessary for the activation of the enzyme pepsin.

  • Peptic cells (or Chief cells) secrete the proenzyme pepsinogen.
  • Mucous neck cells secrete mucus, which helps protect the stomach lining from the corrosive effects of HCl.
  • Goblet cells are primarily found in the intestinal epithelium and also secrete mucus to lubricate the passage of food.
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