Option 1 states that both the assertion (A) and reason (R) are true, and that R is the correct explanation of A. Let`s dissect this option further to understand it better.

The assertion (A) states that Syphilis can be prevented by vaccination. Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. Currently, there is no approved vaccine available for the prevention of syphilis. Therefore, the assertion (A) is false.

The reason (R) states that vaccination triggers the production of antibodies in the body. This is generally true. When a vaccine is administered, it stimulates the immune system to produce antibodies specific to the pathogen or antigen in the vaccine. These antibodies help the body recognize and fight against future infections. So, the reason (R) is true.

Therefore, as the assertion (A) is false but the reason (R) is true, the correct answer is option 4: A is false but R is true.

It is important to note that while vaccination is an effective preventive measure for many diseases, as of now, there is no vaccine available specifically for the prevention of syphilis.