The correct answer is option 4: 1, 2 and 3.

The contribution of the manufacturing sector to environmental degradation occurs during various stages.

Option 1 states that procurement and use of natural resources are the primary contributors to environmental degradation. This is true as manufacturing processes require the extraction of raw materials, often leading to deforestation, habitat destruction, and resource depletion.

Option 2 states that industrial processes and activities contribute to environmental degradation. This is also true, as manufacturing involves activities like energy consumption, waste generation, and emissions of pollutants, all of which have a negative impact on the environment.

Option 3 states that product use and disposal also contribute to environmental degradation. This is also true, as the products manufactured may have a harmful impact on the environment during their use and end up as waste after disposal, leading to pollution and resource depletion.

Therefore, the correct answer is option 4, as all three options (1, 2, and 3) are correct in explaining the contribution of the manufacturing sector to environmental degradation.