Statement I : Too much salt content in diet could be one of the reasons for kidney failure. Statement I : High salt may cause high blood pressure.

Statement I is true as excessive salt intake is a significant risk factor for kidney disease and potential failure. High sodium levels alter the sodium balance, causing kidneys to have reduced function and remove less water. It can also induce glomerular hyperfiltration and detrimental hemodynamic changes. Statement II is also true; high sodium intake is well-established as a primary cause of increased blood pressure and hypertension [3]. Statement II provides the correct explanation for Statement I because hypertension is a leading cause of kidney damage. High blood pressure puts extra strain on the small blood vessels in the kidneys, leading to further damage and eventual renal failure. The relationship is cyclical, as impaired kidneys further struggle to manage sodium and fluid, exacerbating hypertension [4].

Sources

1. [1] https://pmc.ncbi.nlm.nih.gov/articles/PMC8030856/
2. [3] https://www.sciencedirect.com/science/article/pii/S0085253823004933
3. [2] https://www.sciencedirect.com/science/article/abs/pii/S0270929523001171
4. [4] https://pmc.ncbi.nlm.nih.gov/articles/PMC8685361/