Option 1, Price rise, progressive taxation, and the Indo-USA nuclear deal, is the correct answer as it lists the `new` issues that dominate the middle-class led social agenda today. Let`s break down each of these issues for better understanding.

1. Price rise: This refers to the increase in the cost of goods and services, which affects the purchasing power of the middle-class. Inflation and other economic factors contribute to rising prices, and it is a significant concern for the middle-class as it impacts their daily lives and budgets.

2. Progressive taxation: This refers to a tax system where higher-income individuals or households are taxed at a higher rate than those with lower incomes. The middle-class is often concerned with fair and equitable tax systems, and progressive taxation is seen as a way to ensure wealth redistribution and reduce income inequality.

3. Indo-USA nuclear deal: This refers to the civil nuclear agreement between India and the United States. While this may not be directly related to the middle-class social agenda, it can have an impact on the economy and long-term energy security, which are of concern to the middle-class.

Overall, these issues highlight the economic and political concerns of the middle-class and their desire for financial stability, fair taxation, and a secure future