Question map
Which one of the following hormones contains peptide chain?
Explanation
Hormones are chemically classified into steroids, amino acid derivatives, and peptides. Peptide hormones consist of polypeptide chains of amino acids [1]. Insulin is a well-known peptide hormone produced by the pancreas; it consists of 51 amino acids arranged in two disulfide-linked polypeptide chains [1]. While Oxytocin and Corticotropin (ACTH) are also peptide hormones—oxytocin being a nonapeptide and Corticotropin being a 39-amino acid peptide—Insulin is the most classic example of a hormone containing multiple peptide chains [1]. In contrast, Cortisone is a steroid hormone derived from cholesterol and does not contain a peptide chain. Although options 1, 2, and 3 are all technically peptide-based, Insulin is the standard biological reference for a hormone composed of distinct polypeptide chains in most competitive examinations.
Sources
- [1] https://www.ncbi.nlm.nih.gov/books/NBK541112/
- [2] Science , class X (NCERT 2025 ed.) > Chapter 6: Control and Coordination > Do You Know? > p. 111