Which one of the following sets is correctly matched ?

None of the four sets is entirely correct. Option 1 is wrong because diphtheria, pneumonia and leprosy are infectious (largely bacterial) illnesses rather than hereditary disorders, and antibiotics act against bacteria not inherited traits [3]. Option 2 is incorrect because, while syphilis and gonorrhoea are bacterial, AIDS is caused by the HIV virus and is therefore viral, not bacterial [2]. Option 4 is also wrong: polio and Japanese encephalitis are viral, but plague is bacterial (Yersinia pestis) [3]. Option 3 is the closest match—colour blindness and haemophilia are sex‑linked, whereas sickle cell anaemia is a hereditary autosomal disorder—so no option is fully correct and the answer needs review .

Sources

1. [2] Science ,Class VIII . NCERT(Revised ed 2025) > Chapter 3: Health: The Ultimate Treasure > 3.5.1 Treatment of diseases > p. 39
2. [3] https://www.britannica.com/science/bacterial-disease
3. [1] Science , class X (NCERT 2025 ed.) > Chapter 7: How do Organisms Reproduce? > 7.3.3 (d) Reproductive Health > p. 125