Question map
Which one of the following is synthesised in human body that dilates blood vessels and increases blood flow ?
Explanation
The correct answer is option A - Nitric oxide. NO is a molecule naturally produced by the human body and that it acts as a signalling molecule in the cardiovascular system, making blood vessels dilate.[1] Your endothelium itself makes nitric oxide, which acts as a vasodilator, opening up your blood vessels for your blood to flow freely.[2] The cells which line blood vessels release NO in adjoining tissues. The gas has a relaxing effect on muscle cells and thus can increase blood flow.[3] Dr. Murad won the Nobel Prize in 1998 for his discovery that NO is a molecule naturally produced by the human body and that it acts as a signalling molecule in the cardiovascular system, making blood vessels dilate.[4] Nitrous oxide (option B), on the other hand, is primarily known as an anesthetic used in dental clinics and is not synthesized by the body for vasodilation. Options C and D (nitrogen dioxide and nitrogen pentoxide) are not biological signaling molecules synthesized by the human body.
Sources- [1] https://www.thehindu.com/news/cities/Thiruvananthapuram/nobel-laureate-in-thiruvananthapuram-narrates-the-story-of-a-miracle-gas/article5329010.ece
- [3] https://www.downtoearth.org.in/environment/all-in-the-blood-26328
- [4] https://www.thehindu.com/news/cities/Thiruvananthapuram/nobel-laureate-in-thiruvananthapuram-narrates-the-story-of-a-miracle-gas/article5329010.ece
PROVENANCE & STUDY PATTERN
Guest previewThis is a classic 'General Science' question disguised as Chemistry. While technically rooted in the 1998 Nobel Prize in Medicine, it tests the specific confusion between 'Nitric' (biological hero) and 'Nitrous' (laughing gas/pollutant). It rewards precision over general reading.
This question can be broken into the following sub-statements. Tap a statement sentence to jump into its detailed analysis.
- Statement 1: Is nitric oxide (NO) synthesized in the human body and does it dilate blood vessels and increase blood flow?
- Statement 2: Is nitrous oxide (N2O) synthesized in the human body and does it dilate blood vessels and increase blood flow?
- Statement 3: Is nitrogen dioxide (NO2) synthesized in the human body and does it dilate blood vessels and increase blood flow?
- Statement 4: Is nitrogen pentoxide (N2O5) synthesized in the human body and does it dilate blood vessels and increase blood flow?
- Explicitly states NO is naturally produced by the human body.
- Says NO acts as a signalling molecule in the cardiovascular system that makes blood vessels dilate.
- Says the endothelium (cells lining vessels) makes nitric oxide.
- Describes nitric oxide acting as a vasodilator that opens blood vessels to allow blood to flow freely.
- Reports that cells which line blood vessels release NO into adjoining tissues.
- States NO has a relaxing effect on muscle cells and thus can increase blood flow.
This snippet names nitric oxide (NO) as a distinct reactive chemical species and describes its chemical activity, showing it is a wellâdefined biologically relevant molecule.
A student could combine this with basic physiology knowledge (that the body produces many small reactive molecules) to justify checking whether NO is produced endogenously and has signaling roles in humans.
Defines blood pressure and states that constriction of arterioles increases resistance and causes hypertension, linking vessel diameter to blood flow and pressure.
Using the inverse relationship between vessel diameter and resistance, a student could infer that a substance that dilates arterioles would lower resistance and increase flow, motivating investigation of whether NO performs that role.
Explains that hormones and signals can cause contraction of muscles around small arteries, redistributing blood â an example that chemical signals modulate vessel tone.
A student can generalize that endogenous chemicals alter arteriole smooth muscle and therefore seek whether NO is one such endogenous vasomotor mediator.
Describes blood as the transport medium for many substances, implying that dissolved signaling molecules can reach tissues and affect function.
Given blood transports signaling compounds, a student could reasonably hypothesize and then check if NO (or its precursors) is carried or generated near vessels to change blood flow.
This statement analysis shows book citations, web sources and indirect clues. The first statement (S1) is open for preview.
Login with Google to unlock all statements.
This statement analysis shows book citations, web sources and indirect clues. The first statement (S1) is open for preview.
Login with Google to unlock all statements.
This statement analysis shows book citations, web sources and indirect clues. The first statement (S1) is open for preview.
Login with Google to unlock all statements.
This tab shows concrete study steps: what to underline in books, how to map current affairs, and how to prepare for similar questions.
Login with Google to unlock study guidance.
Discover the small, exam-centric ideas hidden in this question and where they appear in your books and notes.
Login with Google to unlock micro-concepts.
Access hidden traps, elimination shortcuts, and Mains connections that give you an edge on every question.
Login with Google to unlock The Vault.