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Q33 (IAS/2024) Science & Technology › Basic Science (Physics, Chemistry, Biology) › Human anatomy physiology Official Key

Which one of the following is synthesised in human body that dilates blood vessels and increases blood flow ?

Result
Your answer: —  Âˇ  Correct: A
Explanation

The correct answer is option A - Nitric oxide. NO is a molecule naturally produced by the human body and that it acts as a signalling molecule in the cardiovascular system, making blood vessels dilate.[1] Your endothelium itself makes nitric oxide, which acts as a vasodilator, opening up your blood vessels for your blood to flow freely.[2] The cells which line blood vessels release NO in adjoining tissues. The gas has a relaxing effect on muscle cells and thus can increase blood flow.[3] Dr. Murad won the Nobel Prize in 1998 for his discovery that NO is a molecule naturally produced by the human body and that it acts as a signalling molecule in the cardiovascular system, making blood vessels dilate.[4] Nitrous oxide (option B), on the other hand, is primarily known as an anesthetic used in dental clinics and is not synthesized by the body for vasodilation. Options C and D (nitrogen dioxide and nitrogen pentoxide) are not biological signaling molecules synthesized by the human body.

Sources
  1. [1] https://www.thehindu.com/news/cities/Thiruvananthapuram/nobel-laureate-in-thiruvananthapuram-narrates-the-story-of-a-miracle-gas/article5329010.ece
  2. [3] https://www.downtoearth.org.in/environment/all-in-the-blood-26328
  3. [4] https://www.thehindu.com/news/cities/Thiruvananthapuram/nobel-laureate-in-thiruvananthapuram-narrates-the-story-of-a-miracle-gas/article5329010.ece
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Q. Which one of the following is synthesised in human body that dilates blood vessels and increases blood flow ? [A] Nitric oxide [B] Nitr…
At a glance
Origin: Mostly Current Affairs Fairness: Low / Borderline fairness Books / CA: 0/10 ¡ 7.5/10
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This is a classic 'General Science' question disguised as Chemistry. While technically rooted in the 1998 Nobel Prize in Medicine, it tests the specific confusion between 'Nitric' (biological hero) and 'Nitrous' (laughing gas/pollutant). It rewards precision over general reading.

How this question is built

This question can be broken into the following sub-statements. Tap a statement sentence to jump into its detailed analysis.

Statement 1
Is nitric oxide (NO) synthesized in the human body and does it dilate blood vessels and increase blood flow?
Origin: Web / Current Affairs Fairness: CA heavy Web-answerable

Web source
Presence: 5/5
"NO is a molecule naturally produced by the human body and that it acts as a signalling molecule in the cardiovascular system, making blood vessels dilate."
Why this source?
  • Explicitly states NO is naturally produced by the human body.
  • Says NO acts as a signalling molecule in the cardiovascular system that makes blood vessels dilate.
Web source
Presence: 5/5
"Your endothelium itself makes nitric oxide, which acts as a vasodilator, opening up your blood vessels for your blood to flow freely."
Why this source?
  • Says the endothelium (cells lining vessels) makes nitric oxide.
  • Describes nitric oxide acting as a vasodilator that opens blood vessels to allow blood to flow freely.
Web source
Presence: 4/5
"The cells which line blood vessels release NO in adjoining tissues. The gas has a relaxing effect onmuscle cells and thus can increase blood flow."
Why this source?
  • Reports that cells which line blood vessels release NO into adjoining tissues.
  • States NO has a relaxing effect on muscle cells and thus can increase blood flow.

Environment, Shankar IAS Acedemy .(ed 10th) > Chapter 19: Ozone Depletion > The chemical reaction > p. 269
Strength: 4/5
“Nitric oxide (NO) catalytically destroys ozone. • Nitric oxide: + ozone; Nitrogen dioxide: + Oxygen • Nitric oxide: Nitrogen dioxide; Nitrogen dioxide: Nitric oxide • Nitric oxide: + monoxide; Nitrogen dioxide: + Oxygen”
Why relevant

This snippet names nitric oxide (NO) as a distinct reactive chemical species and describes its chemical activity, showing it is a well‑defined biologically relevant molecule.

How to extend

A student could combine this with basic physiology knowledge (that the body produces many small reactive molecules) to justify checking whether NO is produced endogenously and has signaling roles in humans.

Science , class X (NCERT 2025 ed.) > Chapter 5: Life Processes > Blood pressure > p. 93
Strength: 5/5
“The force that blood exerts against the wall of a vessel is called blood pressure. This pressure is much greater in arteries than in veins. The pressure of blood inside the artery during ventricular systole (contraction) is called systolic pressure and pressure in artery during ventricular diastole (relaxation) is called diastolic pressure. The normal systolic pressure is about 120 mm of Hg and diastolic pressure is 80 mm of Hg. Blood pressure is measured with an instrument called sphygmomanometer. High blood pressure is also called hypertension and is caused by the constriction of arterioles, which results in increased resistance to blood flow.”
Why relevant

Defines blood pressure and states that constriction of arterioles increases resistance and causes hypertension, linking vessel diameter to blood flow and pressure.

How to extend

Using the inverse relationship between vessel diameter and resistance, a student could infer that a substance that dilates arterioles would lower resistance and increase flow, motivating investigation of whether NO performs that role.

Science , class X (NCERT 2025 ed.) > Chapter 6: Control and Coordination > 6.3 HORMONES IN ANIMALS > p. 109
Strength: 4/5
“The target organs or the specific tissues on which it acts include the heart. As a result, the heart beats faster, resulting in supply of more oxygen to our muscles. The blood to the digestive system and skin is reduced due to contraction of muscles around small arteries in these organs. This diverts the blood to our skeletal muscles. The breathing rate also increases because of the contractions of the diaphragm and the rib muscles. All these responses together enable the animal body to be ready to deal with the situation. Such animal hormones are part of the endocrine system which constitutes a second way of control and coordination in our body.”
Why relevant

Explains that hormones and signals can cause contraction of muscles around small arteries, redistributing blood — an example that chemical signals modulate vessel tone.

How to extend

A student can generalize that endogenous chemicals alter arteriole smooth muscle and therefore seek whether NO is one such endogenous vasomotor mediator.

Science , class X (NCERT 2025 ed.) > Chapter 5: Life Processes > Activity 5.7 > p. 91
Strength: 3/5
“We have seen in previous sections that blood transports food, oxygen and waste materials in our bodies. In Class IX, we learnt about blood being a fluid connective tissue. Blood consists of a fluid medium called plasma in which the cells are suspended. Plasma transports food, carbon dioxide and nitrogenous wastes in dissolved form. Oxygen is carried by the red blood corpuscles. Many other substances like salts, are also transported by the blood. We thus need a pumping organ to push blood around the body, a network of tubes to reach all the tissues and a system in place to ensure that this network can be repaired if damaged.”
Why relevant

Describes blood as the transport medium for many substances, implying that dissolved signaling molecules can reach tissues and affect function.

How to extend

Given blood transports signaling compounds, a student could reasonably hypothesize and then check if NO (or its precursors) is carried or generated near vessels to change blood flow.

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Statement analysis

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Statement analysis

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