Dengue virus is known to cause low platelet count in blood of patient by : 1. interfering in the process of platelet production in bone marrow 2. infecting endothelial cells 3. binding with platelets 4. accumulating platelets in intestine Select the corre

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Q: 12 (CDS-I/2016)
Dengue virus is known to cause low platelet count in blood of patient by :
1. interfering in the process of platelet production in bone marrow
2. infecting endothelial cells
3. binding with platelets
4. accumulating platelets in intestine
Select the correct answer using the code given below :

question_subject: 

Science

question_exam: 

CDS-I

stats: 

0,27,60,36,15,9,27

keywords: 

{'low platelet count': [0, 0, 0, 1], 'dengue virus': [0, 0, 0, 1], 'platelet production': [0, 0, 0, 1], 'platelets': [0, 0, 0, 2], 'blood': [5, 0, 0, 1], 'bone marrow': [3, 0, 1, 2], 'endothelial cells': [0, 0, 0, 1]}

The correct answer is option 4: 1, 2, and 3.

Explanation:

Dengue virus is known to cause low platelet count in the blood of a patient by interfering in the process of platelet production in the bone marrow, infecting endothelial cells, and binding with platelets.

1. Interfering in the process of platelet production in bone marrow: Dengue virus affects the bone marrow, where platelets are produced. It can disrupt the normal production of platelets, leading to a decrease in their numbers.

2. Infecting endothelial cells: Dengue virus can infect and damage the cells lining the blood vessels, known as endothelial cells. This damage can lead to increased permeability of the blood vessels, causing leakage of fluid and platelets into surrounding tissues.

3. Binding with platelets: Dengue virus has been found to directly bind to platelets. This interaction can result in the removal of platelets from circulation, leading to a decrease in their count.

Although the option 4 includes all the correct factors, it is important to note that option 4 does not mention the accumulation of platelets in the intestine (option 4). Therefore, the correct answer should be option 4: 1,