Option 1, Karolina Pliskova, is not the correct answer. Karolina Pliskova did not win the Singles Title in Wimbledon Tennis Championship (Women) in the year 2019.

Option 2, Simona Halep, is the correct answer. Simona Halep won the Singles Title in Wimbledon Tennis Championship (Women) in the year 2019. She defeated Serena Williams in the final, winning 6-2, 6-2. This was Halep`s first Wimbledon title.

Option 3, Serena Williams, is not the correct answer. Although Serena Williams reached the final of the Wimbledon Tennis Championship (Women) in the year 2019, she was defeated by Simona Halep and did not win the Singles Title.

Option 4, Naomi Osaka, is not the correct answer. Naomi Osaka did not win the Singles Title in Wimbledon Tennis Championship (Women) in the year 2019.

In conclusion, Simona Halep won the Singles Title in Wimbledon Tennis Championship (Women) in the year 2019 by defeating Serena Williams.