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Which of the following enzyme(s) is/are released in stomach for protein digestion ?
1. Chymotrypsin
2. Trypsin
3. Pepsin
Select the correct answer using the code given below :
Code :
Explanation
Protein digestion begins in the stomach primarily through the action of the enzyme Pepsin. The gastric glands in the stomach mucosa secrete pepsinogen, an inactive proenzyme. When pepsinogen comes into contact with hydrochloric acid (HCl) secreted by parietal cells, it is converted into the active proteolytic enzyme pepsin. Pepsin then breaks down proteins into smaller peptides like proteoses and peptones.
Trypsin and Chymotrypsin are also protein-digesting enzymes, but they are produced by the pancreas. They are secreted into the small intestine (specifically the duodenum) as inactive precursors (trypsinogen and chymotrypsinogen). They do not function in the stomach's acidic environment; instead, they operate in the alkaline environment of the small intestine. Thus, only statement 3 is correct.