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The correct statement is: 1 and 3.
Let`s analyze each statement:
1. The World Intellectual Property Organisation (WIPO) is a specialized agency of the United Nations System of Organizations. This statement is correct. WIPO is a specialized agency of the United Nations responsible for promoting and protecting intellectual property rights worldwide.
2. WIPO has its headquarters at Rome. This statement is incorrect. The headquarters of WIPO is located in Geneva, Switzerland, not Rome.
3. The Trade Related Aspects of Intellectual Property Rights (TRIPS) Agreement is binding on all WTO members. This statement is correct. The TRIPS Agreement is a binding agreement administered by the World Trade Organization (WTO) and is mandatory for all WTO member countries.
4. Least developed country members of WTO are not required to apply the provisions of TRIPS Agreement for a period of 20 years from the general date of application of the Agreement. This statement is incorrect. Least developed country members of the WTO are given a transition period of 10 years (not 20 years) to implement the provisions of the TRIPS Agreement.
Therefore, the correct answer is: 1 and 3.