In the manufacture of glass, various raw materials are used to achieve the desired properties and characteristics. Option 4, Gypsum, is not used as a raw material in the manufacture of glass.

Option 1, Soda (sodium carbonate), is commonly used as a fluxing agent in the glass-making process. It helps to lower the melting point of the mixture and improves the fluidity of the molten glass.

Option 2, Alumina (aluminum oxide), is used to improve the strength, hardness, and thermal resistance of the glass. It also helps to prevent the glass from becoming too brittle.

Option 3, Borax (sodium borate), is often added as a fluxing agent and to improve the chemical durability of the glass. It helps to make the glass more resistant to acids and water.

Gypsum, on the other hand, is not a common raw material used in glass manufacturing. Gypsum is mainly used in the construction industry as a building material. It is a soft mineral composed of calcium sulfate dihydrate and does not possess the necessary properties to be used in the production of glass.

In conclusion, option 4, Gypsum, is not used as a raw material in the manufacture of glass.