With reference to monoclonal antibodies, often mentioned in news, consider the following statements : I. They are man-made proteins. II. They stimulate immunological function due to their ability to bind to specific antigens. III. They are used in treating viral infections like that of Nipah virus. Which of the statements given above are correct?

States that a gene (DNA) provides information for making a specific protein — establishes proteins are cellular products encoded by genes.

A student could combine this with the fact that antibodies are proteins and then ask whether monoclonal antibodies originate from natural cellular protein synthesis or from laboratory-directed gene/cell methods.

Reinforces that DNA in cells is the information source for making proteins and that changes in information alter the proteins produced.

One could extend this to consider whether monoclonal antibody production involves directing cells (or their DNA) to produce specific antibody proteins artificially.

Explains that medical products (vaccines) can be made in different ways, including newer approaches that instruct our own body cells — illustrates that biomedical agents can be produced or engineered.

Use this as an example that some therapeutic proteins can be produced or engineered by medical/biotech methods, prompting investigation of how monoclonal antibodies are manufactured.

Defines 'man-made' (cultural) environment as creations of humans, giving a clear conceptual distinction between natural biological products and human-made products.

A student can apply this distinction to ask whether monoclonal antibodies are natural products isolated from organisms or human-created/engineered products (thus 'man-made').