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Q122 (NDA-I/2024) Science & Technology › Basic Science (Physics, Chemistry, Biology) Official Key

Bacterial DNA is referred to as naked because it is not associated with :

Result
Your answer: —  Â·  Correct: B
Explanation

Bacterial DNA is referred to as naked because it is not associated with histone proteins. In eukaryotic cells, DNA is wrapped around a core of eight histone proteins to form nucleosomes, which facilitates the packaging of long DNA strands into a compact structure within the nucleus.

In contrast, bacteria are prokaryotes and their genetic material is typically a single, circular double-stranded DNA molecule located in the cytoplasm (the nucleoid region). This DNA lacks the complex wrapping around histones and is not enclosed within a nuclear envelope. Although bacteria contain some histone-like proteins (such as HU proteins) that assist in DNA folding and stabilization, the absence of the characteristic eukaryotic histone association leads to the term "naked DNA." Therefore, Option B is the correct answer as it highlights the fundamental structural difference in DNA packaging between prokaryotes and eukaryotes.

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