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What is R21/Matrix-M™?
Explanation
R21/Matrix-M™ is the second malaria vaccine recommended by the World Health Organization (WHO) for the prevention of malaria in children. It was developed by the University of Oxford and is manufactured by the Serum Institute of India (SII). The vaccine utilizes Novavax's Matrix-M™ adjuvant to enhance the immune response. In October 2023, the WHO recommended its use, noting its high efficacy and cost-effectiveness. The Serum Institute of India has established a massive production capacity for this vaccine, which is expected to significantly bridge the gap between supply and demand in malaria-endemic regions, particularly in Africa. Unlike the RTS,S vaccine, R21 is easier to manufacture at scale. Options B, C, and D are incorrect as Bharat Biotech is not the manufacturer of this vaccine, and it is designed to combat malaria, not AIDS.