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Q138 (UPPCS/2023) Science & Technology › Biotechnology & Health

Which type of vaccine protect against Diphtheria?

Explanation

Diphtheria is caused by the bacterium Corynebacterium diphtheriae, which produces a harmful toxin. The vaccine used to prevent it is a toxoid vaccine. Toxoid vaccines are created by inactivating the toxin (usually with formalin) to make it harmless while retaining its ability to stimulate an immune response against the toxin itself rather than the bacterium. Common examples include the DTaP (Diphtheria, Tetanus, and acellular Pertussis) and Tdap vaccines.

  • Live-attenuated: Uses a weakened form of the pathogen (e.g., MMR, BCG).
  • mRNA: Uses genetic material to instruct cells to produce a protein (e.g., certain COVID-19 vaccines).
  • Viral Vector: Uses a different, harmless virus to deliver genetic code (e.g., Ebola, some COVID-19 vaccines).
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