Jaundice is a symptom often associated with liver disease. When the liver becomes impaired or damaged, it is unable to process bilirubin, a yellow pigment produced by the breakdown of red blood cells. As a result, bilirubin builds up in the blood and causes a yellowing of the skin and eyes, which is known as jaundice.

Option 1: Kidney - The kidney is not directly involved in the production or processing of bilirubin, so kidney disease would not typically cause jaundice.

Option 3: Pancreas - The pancreas plays a role in digestion and the regulation of blood sugar levels but does not directly affect bilirubin metabolism or cause jaundice.

Option 4: Thyroid - The thyroid gland is responsible for regulating metabolism and does not impact bilirubin processing, so thyroid disease would not be a cause of jaundice.

Therefore, the correct answer is option 2, liver.