Both statements referred to in this question are indeed correct:

1. Statement 1 says, "In response to the presence of HCL, secretin is produced from the duodenum." This is true as secretin is a hormone that controls the environment in the duodenum by regulating the production of gastric acid, its secretion is stimulated by the presence of Hydrochloric Acid (HCl) in the stomach. Thus, HCl does result in the production of secretin from the duodenum.

2. Statement 2 indicates, "Enterogastrone is produced in the small intestine in response to the presence of fatty acids." Entergastrone is a hormone that inhibits the muscular and secretory activities of the stomach, preventing it from emptying too quickly, as fatty acids are more difficult for the body to digest. This shows that fatty acids indeed stimulate the production of enterogastrone in the small intestine.

Hence, given the correctness of both the statements, option 3, ’Both 1 and 2’, is the correct answer.