The liver is responsible for synthesizing various substances in the body. When it comes to vitamins, the liver is capable of synthesizing Vitamin-K. Vitamin-K is essential for blood clotting and bone health. It helps in the production of proteins that are involved in blood clotting, making it an important factor in wound healing and preventing excessive bleeding. Additionally, Vitamin-K also plays a role in maintaining strong bones by regulating calcium levels in the body. Although options 1, 2, and 3 (Vitamin-A, Vitamin-E, and Vitamin-D) are all important vitamins, they are not synthesized by the liver. Instead, these vitamins are obtained through the diet or sunlight. Therefore, option 4 (Vitamin-K) is the correct answer in this case.