Option 1, Oxford University, is incorrect because Alison Richard did not serve as the Vice-Chancellor of this university.

Option 2, Cambridge University, is correct. Alison Richard became the first-ever woman Vice-Chancellor of Cambridge University in 2003. She served in this role until 2010. Richard was also notable for being an anthropologist and her work focused on studying the ecology and social behavior of primates.

Option 3, Harvard University, is wrong. Although Alison Richard did work at Yale University, she never took the Vice-Chancellor role at Harvard University.

Option 4, Purdue University, is also not correct. Purdue University, which is located in Indiana, United States, was not led by Alison Richard in any capacity.

To sum up, Alison Richard was the first-ever woman to become Vice-Chancellor at Cambridge University, not Oxford, Harvard, or Purdue.