In the first century AD, India had a thriving trade relationship with the Roman Empire. Many goods from India were exported to Rome during this time. The provided answer states that nutmeg was not a major item of Indian exports to Rome during the first century AD.

Option 1: Pepper was indeed a major item of Indian exports to Rome during this time. It was highly valued for its flavor and was used as a spice.

Option 2: Spikenard was also a major item of Indian exports to Rome. It was used as a fragrance and for medicinal purposes.

Option 3: Tortoiseshell was another significant item exported from India to Rome. It was used to make decorative items and jewelry.

Option 4: The correct answer states that nutmeg was not a major item of Indian exports to Rome. Nutmeg is a spice that was primarily sourced from the Spice Islands, located in the Indonesian archipelago.

Therefore, the correct answer is 4.