The Kyoto Protocol is an international agreement that is associated with option 2: climate change. It was adopted in Kyoto, Japan in 1997 as an extension of the United Nations Framework Convention on Climate Change (UNFCCC). The protocol sets binding targets for industrialized countries to reduce their greenhouse gas emissions in order to mitigate the effects of climate change. It aims to limit the increase in global average temperature to below 2 degrees Celsius above pre-industrial levels. The protocol has been signed and ratified by numerous countries around the world, demonstrating their commitment to addressing climate change. While species conservation, wetland conservation, and medicinal plants are important environmental issues, they are not specifically linked to the Kyoto Protocol.