In the given Venn diagram, we have information about the number of people reading different newspapers. To find the number of people who read at least two newspapers in a population of 10000, we need to look at the overlapping regions in the diagram.

Option 1: 5000 - This option suggests that half of the population reads at least two newspapers. However, looking at the diagram, we can see that the number of people who read two newspapers is less than that.

Option 2: 6000 - This option also suggests that more than half of the population reads at least two newspapers. However, this contradicts the information provided in the Venn diagram.

Option 3: 6250 - This option suggests that slightly more than half of the population reads at least two newspapers. This seems to be a reasonable estimate as it takes into account the overlapping regions in the diagram.

Option 4: 5400 - This is the correct answer based on the information provided in the Venn diagram. It accurately represents the number of people expected to read at least two newspapers in a population of 10000.

Overall, option 4 is the correct answer as it aligns with the information given in the Venn diagram.