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Polio disease is caused by
Explanation
Polio, also known as poliomyelitis, is a highly infectious disease caused by the poliovirus. It is a small, ether-insensitive virus with an RNA genome belonging to the Picornaviridae family. There are three distinct serotypes of the virus: Type 1, Type 2, and Type 3 [3]. The virus primarily enters the body through the mouth, multiplying in the oropharynx and gastrointestinal tract before potentially spreading to the central nervous system. While many infections are asymptomatic, the virus can cause severe symptoms including brain inflammation and acute flaccid paralysis, particularly in the lower limbs. Transmission typically occurs via the fecal-oral route or through contaminated food and water [3]. Prevention is primarily achieved through vaccination, which has successfully eliminated wild poliovirus in many regions [1].
Sources
- [3] https://www.ncbi.nlm.nih.gov/books/NBK558944/
- [1] https://www.cdc.gov/polio/hcp/clinical-overview/index.html