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Option 1 states that vitamin C is essential to make connective tissue in the body. This statement is correct. Vitamin C plays a crucial role in the synthesis of collagen, which is a major component of connective tissue.
Option 2 states that vitamin D is needed for the synthesis of eye pigment. This statement is incorrect. Vitamin D is involved in the regulation of calcium and phosphate metabolism, bone health, and immune function. It does not have a direct role in the synthesis of eye pigment.
Option 3 states that vitamin B12 helps in the maturation of red blood cells (RBC). This statement is correct. Vitamin B12 is essential for the production of healthy RBCs and DNA synthesis.
Option 4 states that vitamin C is required to make use of calcium absorbed from the intestine. This statement is incorrect. While vitamin C does play a role in calcium absorption, it is not necessary for the utilization of calcium absorbed from the intestine.
Therefore, the correct answer is option 2.