Option 1: Kandla is not a major port on the East Coast of India. It is actually a major port located on the West Coast of India, in the state of Gujarat.

Option 2: Vishakhapatnam is the correct answer. It is a major port on the East Coast of India, located in the state of Andhra Pradesh. Vishakhapatnam is one of the busiest ports in India and handles a significant amount of cargo.

Option 3: Karikal is not a major port on the East Coast of India. It is a minor port located in the Union Territory of Puducherry, but it does not have the same level of activity and significance as Vishakhapatnam.

Option 4: Pondicherry (Puducherry) is not a major port on the East Coast of India. It is a Union Territory that has a minor port called Karikal, but it is not as significant as Vishakhapatnam.

In conclusion, the correct answer is option 2: Vishakhapatnam.