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Q112
(IAS/1998)
Science & Technology › Biotechnology & Health › Human genetics and disorders
Answer Verified
Haemophilia is a genetic disorder which leads to
Result
Your answer:
—
·
Correct:
D
Explanation
Haemophilia is an inherited bleeding disorder caused by a deficiency or dysfunction of specific clotting factors (most commonly factor VIII in haemophilia A or factor IX in haemophilia B), which impairs the blood-clotting cascade and results in excessive or prolonged bleeding rather than effective clot formation [1]. Because these clotting proteins are lacking or defective, individuals with haemophilia cannot form stable fibrin plugs to stop bleeding, so the primary clinical consequence is failure of normal blood clotting. This distinguishes haemophilia from conditions that primarily affect red blood cell count or white blood cells, or from cardiac/rheumatic diseases, making “non-clotting of blood” the correct choice.
Sources
- [1] https://www.ncbi.nlm.nih.gov/books/NBK470265/
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