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Option 4 is the correct answer as all the given pairs are correctly matched.
1. Francis Collins - Mapping Human genome: Francis Collins is a physician-geneticist known for his discoveries of disease genes and his leadership of the Human Genome Project (HGP), which aimed to map the complete set of DNA in human body called a genome.
2. Sergey Brin - Google Search Engine: Sergey Brin is one of the co-founders of Google along with Larry Page. They invented Google Search engine, which is the most widely used search engine on the World Wide Web.
3. Jimmy Wales - Wikipedia: Jimmy Wales is the co-founder of Wikipedia, a free online encyclopedia which anyone can edit. It is one of the most popular websites on the internet.
Therefore, all the associations mentioned in the question are accurate, making option 4 ("1, 2 and 3") the correct response.