Question map
With reference to the use of nanotechnology in health sector, which of the following statements is/are correct? 1. Targeted drug delivery is made possible by nanotechnology. 2. Nanotechnology can largely contribute to gene therapy. Select the correct answer using the code given below.
Explanation
The correct answer is option C because both statements are correct.
**Statement 1 is correct:** Nanotechnology has revolutionized the field of drug delivery by providing an effective and targeted delivery of drugs, minimizing side effects, and increasing the therapeutic efficacy of drugs.[1] The application of nanotechnology in drug delivery involves the use of nanoparticles that are designed to carry drugs and deliver them to the desired site of action.[2] Nanoparticles with a size of 1–100 nm are unique since they can pass cell membranes and cause characteristic reactions within cells, affecting both the cell structures and organelles.[3]
**Statement 2 is correct:** Gene therapy, combined with nanotechnology, holds great potential as an innovative approach to tackling numerous severe and untreatable illnesses, namely cancer.[4] Using nanotechnology that enabled mRNA-based COVID-19 vaccines, a new approach to gene therapy may improve how physicians treat inherited forms of blindness.[5] This demonstrates that nanotechnology can indeed contribute largely to gene therapy applications.
Therefore, both statements 1 and 2 are correct, making option C the right answer.
Sources- [1] https://pmc.ncbi.nlm.nih.gov/articles/PMC10536529/
- [2] https://pmc.ncbi.nlm.nih.gov/articles/PMC10536529/
- [3] https://www.frontiersin.org/journals/nanotechnology/articles/10.3389/fnano.2025.1639506/full
- [4] https://www.sciencedirect.com/science/article/abs/pii/S1773224724007524
- [5] https://news.ohsu.edu/2023/01/11/nanotechnology-may-improve-gene-therapy-for-blindness
PROVENANCE & STUDY PATTERN
Full viewThis is a classic 'Applications of Emerging Tech' question. It rewards general awareness over rote memorization. In Science & Tech, if a technology is broadly transformative (like Nanotech or AI), its potential applications in major sectors like Health are almost always 'True' unless the statement implies exclusivity or violates basic physics.
This question can be broken into the following sub-statements. Tap a statement sentence to jump into its detailed analysis.
- Directly states nanotechnology enables effective, targeted delivery of drugs.
- Links targeted delivery with reduced side effects and increased therapeutic efficacy, supporting the statement.
- Explicitly lists 'Targeted drug delivery system' and related mechanisms (active targeting, EPR, controlled release).
- Positions targeted delivery as a central keyword and focus of nanocarrier research, reinforcing the claim.
- Notes nanostructures (1–100 nm) can pass cell membranes and act within cells, a mechanism enabling delivery to specific sites.
- Highlights intrinsic functions of nanomaterials that make them essential in biomedical applications, implying targeted delivery capability.
The modified drug policy explicitly promotes R&D in the drug sector and grants regulatory/exemptions (e.g., newly developed drugs outside price control), a pattern that encourages development of novel drug technologies.
A student could infer that policy incentives for R&D make it more likely that advanced approaches like nanotechnology-based targeted delivery would be researched and developed domestically, and then check regulatory guidelines for such products.
Calls for an inter-ministerial group to boost R&D and for quicker clearance of new drug applications indicate institutional mechanisms exist to evaluate and potentially approve novel drug technologies.
One could use this to reason that if nanotech drug carriers are developed, there is a procedural pathway for their regulatory assessment and market entry; confirm by examining specific regulatory approval criteria.
The pharmaceutical industry has grown substantially (large production share and export orientation), showing infrastructure and expertise that can support development/manufacture of advanced formulations.
A student might combine this industry capacity with knowledge of nanomedicine manufacturing requirements to judge feasibility of producing targeted nanodrugs in the sector.
Discussion of solvents and traditional formulation methods highlights that drug delivery depends on formulation techniques—implying that new formulation technologies (e.g., nanoformulations) are part of the same conceptual space.
One could extend this by comparing standard formulation principles to nanocarrier approaches to see how formulation changes can enable targeted delivery.
The industry’s dependence on imported raw materials (APIs) shows a supply-chain constraint that could affect adoption or scale-up of specialized technologies.
A student could use this to temper expectations: even if nanotech enables targeted delivery technically, supply/dependency issues might affect implementation—check availability of required nano-grade materials.
- Explicitly links nanotechnology (lipid nanoparticles) to a new approach for delivering mRNA for gene therapy.
- Directly states that nanotechnology that enabled mRNA COVID-19 vaccines may improve gene therapy for inherited blindness.
- States that gene therapy combined with nanotechnology holds great potential for treating severe illnesses, indicating a significant contribution.
- Specifically mentions demand for innovative carriers and methodologies—implying nanotech-enabled delivery systems for DNA.
- Describes how nanotechnology has revolutionized drug delivery by enabling targeted delivery using nanoparticles.
- Targeted delivery capability is directly relevant to delivering genetic material in gene therapy applications.
Gives a clear definition of genetic modification/gene technology and describes insertion of foreign genes (gene modification), identifying the technical target that therapies must achieve.
A student can combine this with the basic fact that gene therapy requires safe and effective delivery of genetic material and then ask whether nanotechnology offers such delivery platforms.
Describes India's strong vaccine/biotechnology capabilities and leadership in health biotechnology.
Use this to infer that a robust biotech sector could adopt or scale complementary technologies (e.g., nanotech-based delivery) to advance gene therapies.
Names Biocon as a torchbearer in the biotechnology segment, indicating presence of advanced biotech industry actors.
A student could check whether such firms work on drug-delivery or genetic therapies and whether they partner with nanotech developers to enable gene therapy.
Cartagena Protocol excerpt highlights biosafety concerns and procedures for products of modern biotechnology.
Combine this with the understanding that new delivery methods (like nanocarriers) raise biosafety/regulatory issues relevant to gene therapy adoption and impact.
Notes the scale and limitations of the pharmaceutical industry (large volume production but import dependence for some inputs), implying capacity and gaps in supporting advanced therapies.
A student could use this to judge whether national manufacturing and supply-chain capacity would support scaling nanotechnology-enabled gene therapies.
- [THE VERDICT]: Sitter. This is the 'Hello World' of Nanotechnology preparation. If you studied Nanotech, 'Targeted Drug Delivery' is the very first bullet point in any standard material.
- [THE CONCEPTUAL TRIGGER]: Syllabus keyword 'Awareness in the fields of IT, Space, Computers, robotics, nano-technology'. Focus specifically on the 'Applications' subheading.
- [THE HORIZONTAL EXPANSION]: Don't stop at Health. Memorize applications in: 1) Environment (Nano-remediation, water filters), 2) Agriculture (Nano-urea, precision farming), 3) Energy (Quantum dot solar cells), 4) Electronics (Graphene transistors), 5) Textiles (Silver nanoparticles for anti-odor).
- [THE STRATEGIC METACOGNITION]: For every emerging tech (AI, Nano, Biotech, Blockchain), create a 'Sectoral Matrix': List 3 concrete applications for Health, Agriculture, Environment, and Defense. UPSC asks 'What can it do?', not 'How does it work?'.
Government drug policy references describe measures to give further impetus to R&D in the drug sector, which is the policy context for adopting novel technologies such as nanotech.
High-yield for UPSC: understanding policy levers (incentives, foreign investment rules, R&D support) helps evaluate how new health technologies can be promoted or constrained. Links to governance, science & technology, and economy sections. Prepare by studying policy provisions, R&D incentives, and their practical implications for technology adoption.
- Geography of India ,Majid Husain, (McGrawHill 9th ed.) > Chapter 11: Industries > Drug Policy > p. 62
- Geography of India ,Majid Husain, (McGrawHill 9th ed.) > Chapter 11: Industries > Drug Policy > p. 63
References report India's ranking by volume/value and export capacity, which determine the country's ability to manufacture and scale advanced drug-delivery technologies.
Important for UPSC answers assessing feasibility of new healthcare technologies — connects industry structure, trade/dependence on imports (APIs), and implementation capacity. Useful for questions on health infrastructure and industrial policy; revise industry statistics, supply-chain vulnerabilities, and policy responses.
- Indian Economy, Vivek Singh (7th ed. 2023-24) > Chapter 7: Indian Economy after 2014 > 7.7 Production Linked Incentive Scheme (PLIS) > p. 238
- Geography of India ,Majid Husain, (McGrawHill 9th ed.) > Chapter 11: Industries > PHARMACEUTICAL INDUSTRY > p. 60
Evidence mentions quicker clearance for new drug applications and price/market treatment for newly developed drugs — key for how innovations (e.g., novel delivery systems) reach patients.
Crucial for answering questions on innovation diffusion in health sector: explains how regulatory and pricing frameworks enable or hinder adoption. Integrates with governance, health policy, and pharma regulation topics; study approval processes, pricing rules, and incentives for indigenous R&D.
- Geography of India ,Majid Husain, (McGrawHill 9th ed.) > Chapter 11: Industries > Drug Policy > p. 62
- Geography of India ,Majid Husain, (McGrawHill 9th ed.) > Chapter 11: Industries > Drug Policy > p. 63
Defines gene modification and modern biotechnology, the conceptual foundation for any gene-based interventions such as gene therapy.
High-yield for UPSC as it clarifies what constitutes gene technology vs. conventional breeding; links to ethics, biosafety and policy debates on genetic interventions. Master by understanding definitions, processes (transgene insertion), and policy implications to answer questions on biotechnology regulation and applications.
- Indian Economy, Nitin Singhania .(ed 2nd 2021-22) > Chapter 9: Agriculture > GENETICALLY MODIFIED (GM) CROPS > p. 301
Frames the safety, environmental and regulatory concerns around modern biotechnology products that would include gene therapies.
Important for GS Paper topics on environment, international agreements and policy. Questions often probe regulatory frameworks and risk management for biotech advances; study the Protocol's aims, biosafety principles and national implementation measures.
- Environment, Shankar IAS Acedemy .(ed 10th) > Chapter 28: International Organisation and Conventions > Cartagena Protocol on Biosafety to the Convention on Biological Diversity > p. 391
Illustrates India's industrial and institutional capacity in biotech and health-sector production, relevant when assessing adoption or scaling of advanced health technologies.
Useful for answers on India's health infrastructure, biotech industry and manufacturing policy (e.g., PLI, major firms). UPSC questions may ask about nation's capacity to adopt new medical technologies; prepare by linking industry facts, major firms and policy supports.
- Science ,Class VIII . NCERT(Revised ed 2025) > Chapter 3: Health: The Ultimate Treasure > India's Role in Vaccine Production > p. 39
- Geography of India ,Majid Husain, (McGrawHill 9th ed.) > Chapter 11: Industries > 19. The Biocon Group > p. 110
- Indian Economy, Vivek Singh (7th ed. 2023-24) > Chapter 7: Indian Economy after 2014 > 7.7 Production Linked Incentive Scheme (PLIS) > p. 238
Since they asked about Drug Delivery (Liposomes/Dendrimers), the next logical question is on 'Theranostics' (Therapy + Diagnostics combined) or specific materials like 'Quantum Dots' (used for medical imaging) and 'Gold Nanoshells' (cancer thermal therapy).
The 'Possibility Heuristic': In Science & Tech, statements using modal verbs like 'can', 'may', 'possible', or 'contribute to' are almost always True. Unless the statement contains an extreme restrictor (e.g., 'can ONLY be done by...'), mark it correct. The examiner cannot easily prove that a nascent technology *cannot* do something.
Bridge to GS-3 Agriculture & Economy: Connect Nanotech in health to 'Nano-Urea' in Agriculture. Just as nanotech reduces drug dosage/side-effects in humans, Nano-Urea reduces fertilizer runoff and subsidy burden in the economy. It's the same principle of 'Targeted Delivery' applied to plants.