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With reference to carbon nanotubes, consider the following statements : 1. They can be used as carriers of drugs and antigens in the human body. 2. They can be made into artificial blood capillaries for an injured part of human body. 3. They can be used in biochemical sensors. 4. Carbon nanotubes are biodegradable. Which of the statements given above are correct ?
Explanation
The correct answer is Option 3 (1, 3 and 4 only). Carbon nanotubes (CNTs) are cylindrical molecules with unique physicochemical properties that make them highly versatile in biotechnology and medicine.
- Statement 1 is correct: CNTs possess a high surface area-to-volume ratio, allowing them to be functionalized with ligands to act as efficient carriers for drugs and antigens, delivering them directly to targeted cells.
- Statement 3 is correct: Due to their exceptional electrical conductivity and sensitivity to surface adsorption, they are widely used in biochemical sensors to detect glucose, proteins, or DNA sequences.
- Statement 4 is correct: Research has shown that CNTs can be biodegraded by certain enzymes, such as oxidative enzymes (e.g., fungal peroxidase), which mitigates concerns regarding long-term toxicity.
- Statement 2 is incorrect: While CNTs are used in tissue engineering scaffolds, they are not currently used to create functional artificial blood capillaries, as this requires complex biological integration beyond the scope of simple nanotubes.
PROVENANCE & STUDY PATTERN
Guest previewThis is a classic 'Emerging Tech' question where the 'Can be' heuristic rules supreme. While NCERT Class X (Carbon) provides the structural basics (allotropes), the applications are pure Current Affairs. The strategy here is not to find a book that lists all 4 uses, but to understand that in Nanotech, 'possibility' is broad. If it doesn't violate a law of physics, it's likely correct.
This question can be broken into the following sub-statements. Tap a statement sentence to jump into its detailed analysis.
- Statement 1: Can carbon nanotubes be used as carriers for drugs and antigens in the human body?
- Statement 2: Can carbon nanotubes be fabricated into artificial blood capillaries for repairing injured human tissue?
- Statement 3: Can carbon nanotubes be used in biochemical sensors (biosensors)?
- Statement 4: Are carbon nanotubes biodegradable in biological environments or the human body?
- Explicitly states experimental evidence (in vitro and in vivo) showing CNTs can improve treatment effects and reduce side/toxic effects of drugs loaded on them.
- Directly concludes this indicates a promising future for CNTs to be used as drug carriers, while noting pharmacological/toxicological profiles must be clarified.
- Describes CNTs as versatile and effective drug delivery carriers for many small molecule drugs.
- Specifically notes applicability to both cancer and non-anticancer drug indications, supporting their general use as carriers.
Mentions fullerenes (C60) as a class of carbon allotropes related to other carbon nanostructures; shows carbon can form distinct cage/novel structures.
A student could note that nanotubes are another carbon allotrope similar to fullerenes and therefore may share properties (size, hollow structure) that make them candidates for carrying molecules.
Describes graphene aerogel, a novel porous carbon material with high absorbance and use in environmental cleanup — an example of engineered carbon materials used to take up/hold substances.
One could infer that engineered carbon materials can adsorb and carry other substances and thus hypothesize nanotubes might carry drugs/antigens by adsorption or encapsulation.
Explains that functional groups on carbon chains determine properties regardless of chain length — shows that adding functional groups to carbon frameworks changes interactions.
A student can extend this to the idea that functionalising carbon nanotubes (attaching groups) could tailor their solubility/biocompatibility and drug-binding — key for carrier design.
Highlights carbon's tetravalency and catenation leading to many carbon compounds and bonds with elements like oxygen, nitrogen, etc.
This suggests carbon nanostructures can form covalent or noncovalent interactions with biological molecules or functional groups, implying routes to attach drugs/antigens.
Describes blood as a transport medium that carries dissolved substances throughout the body.
Using the basic fact that the bloodstream transports carried agents, a student could combine this with nanotube carrier potential to assess delivery feasibility and need for biocompatibility/size considerations.
This statement analysis shows book citations, web sources and indirect clues. The first statement (S1) is open for preview.
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This statement analysis shows book citations, web sources and indirect clues. The first statement (S1) is open for preview.
Login with Google to unlock all statements.
This statement analysis shows book citations, web sources and indirect clues. The first statement (S1) is open for preview.
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