Question map
What is the application of Somatic Cell Nuclear Transfer Technology ?
Explanation
Somatic Cell Nuclear Transfer (SCNT) technology allows the generation of clones of animals about which substantial knowledge of their performance exists.[1] The technique involves deposition of a somatic cell into an enucleated oocyte resulting in an embryo[2], which is then implanted into a foster or surrogate mother.[3] Somatic cells can be cryopreserved and used in SCNT for reproductive cloning, which has been successful for many domestic mammalian species (e.g. cattle, sheep, horses, pigs and goats).[4] Since the birth of Dolly in 1996, cloning has been achieved for various species, and up to 2004, about 1,500 calves had been produced through SCNT.[5] This technology is specifically designed for reproductive cloning and has no application in producing biolarvicides, manufacturing biodegradable plastics, or directly producing disease-free organisms. Therefore, option C is the correct answer.
Sources- [1] https://www.fao.org/4/j8959e/j8959e.pdf
- [2] https://www.fao.org/fileadmin/user_upload/animal_genetics/docs/CGRFA-18-21-10_2_Inf1_forPDF.pdf
- [3] https://www.fao.org/4/j8959e/j8959e.pdf
- [4] https://www.fao.org/fileadmin/user_upload/animal_genetics/docs/CGRFA-18-21-10_2_Inf1_forPDF.pdf
- [5] https://www.fao.org/4/i2300e/i2300e03.pdf
PROVENANCE & STUDY PATTERN
Full viewThis is a classic 'Term-Definition' match. SCNT is simply the technical name for the method used to create 'Dolly the Sheep'. The strategy is simple: when reading about a famous scientific outcome (Cloning), always memorize the specific technical process behind it.
This question can be broken into the following sub-statements. Tap a statement sentence to jump into its detailed analysis.
- Statement 1: Is Somatic Cell Nuclear Transfer (SCNT) technology used for production of biolarvicides?
- Statement 2: Is Somatic Cell Nuclear Transfer (SCNT) technology used for manufacture of biodegradable plastics?
- Statement 3: Is Somatic Cell Nuclear Transfer (SCNT) technology used for reproductive cloning of animals?
- Statement 4: Is Somatic Cell Nuclear Transfer (SCNT) technology used for production of organisms free of diseases?
Describes tissue culture where cells or tissues are removed and grown in artificial media to produce new organisms or many copies (callus → plantlets).
A student could extend this by noting tissue/cell-based propagation techniques are used to mass-produce biological materials and then ask whether SCNT is another cell-based method that could analogously produce organisms that serve as biolarvicides.
Explains that multicellular organisms have specialised reproductive strategies and that reproduction can be engineered by manipulating specific cell types.
One could use this to reason that cloning methods (like SCNT) alter reproductive processes and then check whether cloned organisms are used to generate organisms or secretions employed as larvicides.
Discusses DNA copying, cellular apparatus, and that cellular division and organisation are required for producing viable copies—highlighting that manipulating nuclei and cells affects organismal replication.
This provides a conceptual link to nuclear transfer (moving nuclei between cells) and suggests checking whether such nuclear manipulations are applied to create organisms or cell-lines used in biolarvicide production.
Summarises the Cartagena Protocol governing movement of Living Modified Organisms (LMOs) from modern biotechnology, implying regulatory attention to biotechnology-derived organisms.
A student could use this to pursue whether products labelled as biolarvicides fall under LMOs and whether techniques like SCNT (a modern biotech method) are mentioned in regulatory or product literature for such biocontrol agents.
Also states the objective of protecting against adverse effects of LMOs from modern biotechnology and regulating their import/export.
This supports checking international/regulatory sources to see if SCNT-derived organisms are categorized among LMOs used as biolarvicides, enabling verification or elimination of the statement.
Mentions that new types of plastics said to be biodegradable are available, indicating research/technology is applied to produce biodegradable plastics.
A student could look up what kinds of technologies (chemical polymerization, microbial fermentation, genetic engineering) are cited in descriptions of such biodegradable plastics to see if SCNT appears.
Gives a clear definition of 'biodegradable' as breakdown by natural processes, which frames the kinds of biological or chemical routes that could produce or degrade such plastics.
Use this definition plus knowledge of SCNT (a cloning technique) to judge whether SCNT logically connects to producing materials that must be broken down by natural processes.
Describes bioremediation techniques that rely on microorganisms (and engineered 'mixtures of bacteria') to degrade pollutants, showing biological approaches to plastic/pollutant problems tend to use microbes/enzymes.
A student could infer that microbial or enzymatic biotech is a common biological route for plastics issues and then check whether SCNT (an animal-cell cloning method) is used in similar applications.
Lists environmental problems caused by non-biodegradable plastics, highlighting the demand and incentive to develop biodegradable alternatives.
Knowing there is demand, a student could survey typical R&D methods used to create biodegradable plastics (e.g., biopolymers, bacterial synthesis) to see if SCNT appears among them.
Shows regulatory pressure (bans on single-use plastics) that motivates development and manufacture of biodegradable plastics.
Use the regulatory context to investigate industrial approaches adopted in response (chemical bioplastics, microbial production) and whether SCNT features in industry practice.
- Explicitly states somatic cells can be used in SCNT for reproductive cloning.
- Lists successful cloning of multiple livestock species using SCNT, directly tying the technique to animal reproductive cloning.
- Describes SCNT as a technology that generates clones of animals.
- Explains the SCNT procedure and that the embryo is implanted into a foster or surrogate mother, indicating reproductive cloning.
- Refers to transferring SCNT embryos into recipients, showing use of SCNT to produce embryos for implantation.
- Notes commercial services that generate cloned animals from skin samples using SCNT, demonstrating practical reproductive cloning of animals.
Explains that reproduction fundamentally involves making copies of DNA inside cells — cloning would therefore be a process focused on producing an identical DNA copy.
A student can use this rule plus basic outside knowledge that SCNT attempts to create an organism by transferring a donor nucleus (DNA) into a recipient cell, and so judge whether SCNT fits the idea of producing an identical DNA-based individual.
States that DNA copying is not perfectly accurate and sexual reproduction generates variation — implying that methods that bypass gamete fusion could produce less variation (i.e., more similar/identical offspring).
A student could contrast sexual reproduction (variation-generating) with a technique that directly copies a somatic nucleus (SCNT) to assess whether SCNT would produce genetically identical animals.
Lists forms of reproduction and notes that some modes (like vegetative propagation or regeneration) produce very similar or identical individuals — giving examples of non-sexual ways to make near-exact copies.
Using this pattern, a student can classify SCNT as another non-sexual, laboratory-based route to produce an organism similar to vegetative propagation and then seek whether SCNT is used to produce whole animals.
Explains gametes carry half the genetic material and fusion restores a full set — highlighting that most reproductive techniques rely on gametes, so technologies that avoid gametes are distinct.
A student can use this to distinguish SCNT (which uses a somatic nucleus rather than gamete fusion) from standard reproductive methods and thus infer whether SCNT could be a route to create whole animals.
Mentions assisted reproductive technologies used in animal conservation (artificial insemination, embryo transfer, cryopreservation), indicating that reproductive technologies exist to produce or manage offspring.
A student could extend this by noting that SCNT, if available, would be another assisted reproductive/biotechnological tool to produce animals and so check whether SCNT is used in that same practical context.
Tissue culture is cited as a technique that can produce many plants from one parent in disease-free conditions.
A student could compare tissue-culture methods (which produce disease-free clones) with SCNT (a cloning approach) to ask whether similar in vitro cloning could yield disease-free organisms.
The text notes availability of disease-free germplasm and mentions embryo transfer technology as a reproductive tool to improve genetic stock.
One could extend this pattern to examine whether reproductive technologies like SCNT are used analogously to provide disease-free germplasm in animals.
States that a single cell type in an organism can, under suitable conditions, grow and make other cell types.
This general rule supports the plausibility that transferring a nucleus into an enucleated cell (as in SCNT) could regenerate a whole organism, prompting investigation of whether that organism would be disease-free.
Emphasises that reproduction involves creating DNA copies and cellular apparatus.
A student could reason that because SCNT copies an individual’s DNA, any genetic disease present in donor DNA may be reproduced rather than eliminated, so SCNT may not guarantee disease-free progeny.
Notes that DNA copying is imperfect and generates variation in populations.
One could use this to argue that cloning (precise DNA copying via SCNT) might reduce variation but not necessarily remove disease-causing mutations, leading to targeted questions about genetic vs. non-genetic disease transmission in SCNT-derived organisms.
- [THE VERDICT]: Sitter. If you knew 'Dolly the Sheep' was a clone, you likely read about SCNT. If not, the term 'Nuclear Transfer' is a strong biological hint.
- [THE CONCEPTUAL TRIGGER]: General Science > Biotechnology > Reproductive Technologies. Specifically, the mechanism of Cloning.
- [THE HORIZONTAL EXPANSION]: Memorize these Tech-Application pairs: 1. CRISPR-Cas9 = Gene Editing (Molecular Scissors). 2. Mitochondrial Replacement Therapy = Three-parent baby (preventing mitochondrial disease). 3. iPSC (Induced Pluripotent Stem Cells) = Turning adult cells back into stem cells (Regenerative medicine). 4. Meristem Culture = Virus-free plants (Option D).
- [THE STRATEGIC METACOGNITION]: UPSC creates options by mixing applications of different technologies. Option A is Biocontrol, Option B is Material Science/Microbes, Option D is Tissue Culture. You must map the 'Mechanism' (Nuclear Transfer) to the 'Function' (Cloning).
References [5] and [9] describe the Cartagena Protocol governing movement and biosafety of LMOs—directly relevant to international regulation of biotechnology products such as biological control agents.
High-yield for UPSC environment and policy topics: explains international biosafety governance, transboundary movement controls, and risk considerations for biotech products. Connects to biodiversity conventions, national biosafety frameworks, and questions on regulation of emerging technologies; useful for policy-analysis and ethics-type questions.
- Environment and Ecology, Majid Hussain (Access publishing 3rd ed.) > Chapter 5: Biodiversity and Legislations > cartagEna Protocol. > p. 10
- Environment, Shankar IAS Acedemy .(ed 10th) > Chapter 28: International Organisation and Conventions > Objective > p. 391
Reference [7] explains tissue culture as a laboratory method to grow plants from cells or tissues—illustrative of biotechnological production methods distinct from SCNT.
Important for UPSC coverage of applied biotechnology in agriculture and environment: clarifies common lab propagation techniques, their applications (disease-free planting material), and contrasts with other biotech methods. Enables answers on biotechnology applications, biosafety, and agricultural productivity.
- Science , class X (NCERT 2025 ed.) > Chapter 7: How do Organisms Reproduce? > Tissue culture > p. 118
References [2] and [10] discuss specialized cells and why multicellular organisms use complex reproductive strategies—background needed to understand why SCNT (a cloning method) is biologically distinct from normal reproduction.
Foundational biology concept useful across GS papers: helps distinguish natural reproduction, cloning techniques, and limits of cellular manipulation. Enables conceptual answers on ethics, feasibility, and implications of biotechnologies such as cloning or organismal engineering.
- Science , class X (NCERT 2025 ed.) > Chapter 7: How do Organisms Reproduce? > How do Organisms Reproduce? CHAPTER7 > p. 116
- Science , class X (NCERT 2025 ed.) > Chapter 7: How do Organisms Reproduce? > 7.1 DO ORGANISMS CREATE EXACT COPIES OF THEMSEL THEMSELVES? > p. 114
The statement concerns 'biodegradable plastics'; several references define and discuss biodegradable materials and the availability of biodegradable plastics.
High-yield for environment sections: understanding the definition and distinguishing features of biodegradable materials helps answer questions on waste management, policy measures, and technological claims. Connects to topics on pollution, materials science in environmental context, and regulatory responses. Useful for elimination-style questions and for explaining policy rationale.
- Environment and Ecology, Majid Hussain (Access publishing 3rd ed.) > Chapter 12: Major Crops and Cropping Patterns in India > Glossary > p. 101
- Science , class X (NCERT 2025 ed.) > Chapter 13: Our Environment > Activity 13.6 > p. 214
Context around biodegradable plastics is driven by problems caused by conventional plastics (drain choking, harm to animals, persistence in marine environments) described in the references.
Important for GS Paper III/Environment: knowing specific impacts of plastic pollution allows candidates to link technological solutions (like biodegradable plastics) to real-world problems and policy measures (bans, thickness rules). Enables analytical answers and policy suggestions in mains and interview.
- Environment, Shankar IAS Acedemy .(ed 10th) > Chapter 5: Environmental Pollution > 5.12.2. Plastics as a Waste Material in Land Environment > p. 97
- Environment, Shankar IAS Acedemy .(ed 10th) > Chapter 5: Environmental Pollution > 5.12.1. Plastics as a Waste Material in Marine Environment > p. 96
References describe ex-situ bioremediation (landfarming, biopiles, microbial mixtures) that aim to stimulate biodegradative microorganisms — directly relevant to the concept of biodegradation of pollutants.
Useful for technical questions on how biodegradable waste or pollutants are treated; links biotechnology/ microbiology to environmental management. Prepares candidates to discuss methods, their suitability and limitations, and to compare in-situ vs ex-situ approaches in answers.
- Environment, Shankar IAS Acedemy .(ed 10th) > Chapter 5: Environmental Pollution > bi Ex situ bioremediation techniques > p. 100
SCNT involves transferring a nucleus (DNA) between cells, so understanding how cells copy DNA and the error/variation rates is directly relevant to cloning outcomes.
High-yield for UPSC because it connects basic molecular processes to applied biotechnologies (cloning, genetic modification). Mastering this helps answer questions on biotechnology ethics, conservation techniques and limitations of cloning; useful for linking biology basics to policy and conservation scenarios.
- Science , class X (NCERT 2025 ed.) > Chapter 7: How do Organisms Reproduce? > 7.1 DO ORGANISMS CREATE EXACT COPIES OF THEMSEL THEMSELVES? > p. 113
- Science , class X (NCERT 2025 ed.) > Chapter 7: How do Organisms Reproduce? > 7.3.1 Why the Sexual Mode of Reproduction? > p. 119
- Science , class X (NCERT 2025 ed.) > Chapter 7: How do Organisms Reproduce? > What you have learnt > p. 126
Option D (Production of organisms free of diseases) is the specific definition of 'Meristem Culture' or 'Micropropagation' in plants (NCERT Class 12 Biology). This is a high-probability future question.
Deconstruct the name: 'Somatic Cell' (Body cell) + 'Nuclear Transfer' (Moving the DNA core). If you move a body cell's DNA into an egg, you are copying the genetic blueprint of an existing adult. This is the definition of Cloning. Biolarvicides and Plastics are chemical/industrial products, not 'Nuclear Transfer' processes.
Connect SCNT to GS-4 (Ethics) and GS-3 (Science Policy). The debate on 'Therapeutic Cloning' (creating tissues) vs 'Reproductive Cloning' (creating babies) is a major ethical dilemma. India's DBT Guidelines prohibit human reproductive cloning.