Despotism refers to a form of government where a single ruler or a small group of rulers have absolute power and authority over the citizens. Option 1, which states that despotism is possible in a one party state, is correct. In a one party state, there is only one political party that holds power, and this party may suppress opposition and dissent, leading to a concentration of power in the hands of a single ruler or group. Options 2 and 3, which suggest that despotism is possible in a two-party or multi-party state, are incorrect. In these states, power is usually distributed among different political parties and individuals, creating a system of checks and balances that limits the potential for absolute rule. The option 4, which combines options 2 and 3, is also incorrect.